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|
UDP-glucuronate + 3-O-[alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-beta-D-Gal-(1rarr3)-beta-D-Gal-(1rarr4)-beta-D-Xyl]-L-seryl-[protein] <=> 3-O-[beta-D-GlcA-(1rarr3)-alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-beta-D-Gal-(1rarr3)-beta-D-Gal-(1rarr4)-beta-D-Xyl]-L-seryl-[protein] + UDP + H+
|
2.4.1.225
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
|
–
|
| |
MetaCyc:
2.4.1.225-RXN
|
|
|
|
[heparan_sulfate]-alpha-D-N-sulfoglucosamine_6-O-sulfate + 3''-phosphoadenylyl-sulfate <=> [heparan_sulfate]-alpha-D-N-sulfoglucosamine_3,6-O-bissulfate + adenosine_3,5''-bisphosphate + H+
|
2.8.2
|
–
|
| |
MetaCyc:
RXN-11563
|
|
|
|
[heparan_sulfate]-alpha-L-iduronate + 3''-phosphoadenylyl-sulfate <=> [heparan-sulfate]-2-O-sulfo-alpha-L-iduronate + adenosine_3,5''-bisphosphate + H+
|
2.8.2
|
–
|
| |
MetaCyc:
RXN-11558
|
|
|
|
UDP-N-acetyl-D-glucosamine + 3-O-[beta-D-GlcA-(1rarr3)-beta-D-Gal-(1rarr3)-beta-D-Gal-(1rarr4)-beta-D-Xyl]-L-seryl-[protein] <=> 3-O-[alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-beta-D-Gal-(1rarr3)-beta-D-Gal-(1rarr4)-beta-D-Xyl]-L-seryl-[protein] + H+ + UDP
|
2.4.1.223
glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
|
–
|
| |
MetaCyc:
2.4.1.223-RXN
|
|
|
|
[heparan_sulfate]-N-sulfoglucosamine + 3''-phosphoadenylyl-sulfate <=> [heparan_sulfate]-alpha-D-N-sulfoglucosamine_3-O-sulfate + adenosine_3,5''-bisphosphate + H+
|
2.8.2.23
[heparan sulfate]-glucosamine 3-sulfotransferase 1
|
–
|
| |
MetaCyc:
2.8.2.23-RXN
|
|
|
|
[heparan_sulfate]-glucosamine + 3''-phosphoadenylyl-sulfate <=> [heparan_sulfate]-glucosamine_3-sulfate + adenosine_3,5''-bisphosphate + H+
|
2.8.2.23
[heparan sulfate]-glucosamine 3-sulfotransferase 1
2.8.2.29
[heparan sulfate]-glucosamine 3-sulfotransferase 2
2.8.2.30
[heparan sulfate]-glucosamine 3-sulfotransferase 3
|
–
–
–
|
| |
BRENDA:
BR37020;
BS360434
MetaCyc:
2.8.2.30-RXN
|
|
|
|
[heparan_sulfate]-N-sulfoglucosamine + 3''-phosphoadenylyl-sulfate <=> [heparan_sulfate]-alpha-D-N-sulfoglucosamine_3-O-sulfate + adenosine_3,5''-bisphosphate + H+
|
2.8.2.29
[heparan sulfate]-glucosamine 3-sulfotransferase 2
|
–
|
| |
MetaCyc:
2.8.2.29-RXN
|
|
|
|
[heparan_sulfate]-N-sulfoglucosamine + 3''-phosphoadenylyl-sulfate <=> [heparan_sulfate]-alpha-D-N-sulfoglucosamine_6-O-sulfate + adenosine_3,5''-bisphosphate + H+
|
2.8.2
|
–
|
| |
MetaCyc:
RXN-11562
|
|
|
|
[heparan-sulfate]-beta-D-glucuronate <=> [heparan_sulfate]-alpha-L-iduronate
|
5.1.3.17
heparosan-N-sulfate-glucuronate 5-epimerase
|
–
|
| |
MetaCyc:
5.1.3.17-RXN
|
|
|
|
[heparan_sulfate]-glucosamine + 3''-phosphoadenylyl-sulfate <=> [heparan_sulfate]-N-sulfoglucosamine + adenosine_3,5''-bisphosphate
|
2.8.2.8
[heparan sulfate]-glucosamine N-sulfotransferase
|
–
|
| |
BRENDA:
BR48122
KEGG:
R02122
MetaCyc:
HEPARITIN-SULFOTRANSFERASE-RXN
|
|
|
|
3-O-[alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-beta-D-Gal-(1rarr3)-beta-D-Gal-(1rarr4)-beta-D-Xyl]-L-seryl-[protein] <=> Heparan
|
not assigned
|
–
|
| |
MetaCyc:
RXN-16327
|
|
|
|
UDP-N-acetyl-D-glucosamine + 3-O-[beta-D-GlcA-(1rarr3)-alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-beta-D-Gal-(1rarr3)-beta-D-Gal-(1rarr4)-beta-D-Xyl]-L-seryl-[protein] <=> 3-O-[alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-alpha-D-GlcNAc-(1rarr4)-beta-D-GlcA-(1rarr3)-beta-D-Gal-(1rarr3)-beta-D-Gal-(1rarr4)-beta-D-Xyl]-L-seryl-[protein] + UDP + H+
|
2.4.1.224
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
|
–
|
| |
MetaCyc:
2.4.1.224-RXN
|
|
|
|
[heparan_sulfate]-N-acetyl-alpha-D-glucosamine + H2O <=> [heparan_sulfate]-glucosamine + acetate + H+
|
3.1.1
|
–
|
| |
MetaCyc:
RXN-11557
|
|
